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Megacolon 

1. Colon has poor motility and becomes dilated as impacted feces accumulate.
   2. Exacerbated by dry hard stool.
   3. Affected animals may strain to defecate, have diarrhea after prolonged straining, vomit, become lethargic, and have a decreased appetite.

 

Treatment: Goals of treatment are to soften feces for easier passage and increase colonic motility if possible.

 

   1. Maintain adequate hydration - provide plenty of fresh water at home, dehydrated animals may require subcutaneous or intravenous fluids.
   2. Laxatives

   1. mineral oil - 1/2 teaspoon twice daily
   2. petroleum jelly - 1/2 teaspoon twice daily
   3. Laxatone - 1/2 to 1 teaspoon twice daily

   1. Docusate Sodium (DSS) soft gel capsules

   1. draws fluid into stool
   2. once or twice daily

   1. Cisapride (Propulsid)

   1. may increase colonic motility
   2. 1/2 of a 10 mg tablet twice daily ($1 per day)
   3. also available in transdermal gel form

   1. Lactulose liquid

   1. softens stool - may cause diarrhea in higher doses
   2. 1/4 teaspoon (1 ml) 2 to 3 times daily

   1. Hi fiber diet

   1. draws fluid into stool
   2. added bulk may make it harder to pass stool
   3. prescription diets - W/D, DM
   4. 1/2 teaspoon metamucil mixed with 1/2 can of food twice daily - do not use citrus flavor

   1. Deobstipation - manual extraction of impacted feces may occasionally be required
   2. Enema - occasionally required
   3. Surgery

   1. in cases that are refractory to medical management, partial or total resection of the colon may be the final option